The Mechanism of Action of Anastrozole

Anastrozole is a medication commonly used in the treatment of breast cancer. It belongs to a class of drugs known as aromatase inhibitors, which work by inhibiting the enzyme aromatase. This enzyme is responsible for converting androgens into estrogens in the body. By blocking aromatase, anastrozole effectively reduces the levels of estrogen in the blood, which can help slow down or even stop the growth of hormone receptor-positive breast cancer cells.

How Does Anastrozole Work?

When taken orally, anastrozole is rapidly absorbed into the bloodstream and reaches peak concentrations within 2 hours. It is highly selective in its action, targeting only the aromatase enzyme while leaving other enzymes unaffected. By binding to the active site of aromatase, anastrozole prevents the conversion of androgens into estrogens. This results in decreased estrogen levels in the body, which can help prevent the growth and spread of estrogen-sensitive breast cancer cells.

Benefits of Anastrozole

Anastrozole has been shown to be effective in reducing the risk of recurrence in postmenopausal women with early-stage breast cancer. It is also used as a first-line treatment for advanced breast cancer in postmenopausal women. By inhibiting the production of estrogen, anastrozole helps to deprive cancer cells of the hormone they need to grow and divide. This can result in tumor shrinkage and improved survival rates in patients with hormone receptor-positive breast cancer.

In conclusion, anastrozole works by inhibiting the enzyme aromatase, thereby reducing estrogen levels in the body. This mechanism of action makes it an effective treatment option for https://anastrozoleonline.com/medicament/anastrozol-ratiopharm-1-mg-filmtabletten/ hormone receptor-positive breast cancer. By understanding how anastrozole works, healthcare providers can better tailor treatment plans for patients with this type of cancer.